Invitrogen™ RGS17 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA584296

Product Code. 16391245

Description

Immunogen sequence: RDSFPRFLNS QIYKSFVEST AGSSSES Highest antigen sequence indentity to the following orthologs: Mouse - 81%, Rat - 89%.

This gene encodes a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.

Specifications

• Antigen: RGS17
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RGS17
• Gene Alias: 6430507P11Rik; hRGS17; regulator of G-protein signaling 17; regulator of G-protein signaling Z2; regulator of Gz-selective protein signaling 2; Rgs17; RGS-17; Rgsz2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 26575
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry, Immunofluorescence
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9UGC6
• Gene Symbols: RGS17
• Immunogen: Recombinant protein corresponding to Human RGS17. Recombinant protein control fragment (Product #RP-105046).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG