Invitrogen™ RGS1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA529579

Product Code. 13443747

Description

Recommended positive controls: K562. Predicted reactivity: Mouse (86%), Rhesus Monkey (97%), Bovine (90%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a member of the regulator of G-protein signaling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.

Specifications

• Antigen: RGS1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RGS1
• Gene Alias: 1R20; B-cell activation protein BL34; BL34; Early response protein 1R20; epididymis secretory protein Li 87; HEL-S-87; IER1; immediate-early response 1, B-cell specific; IR20; Regulator of G-protein signaling 1; regulator of G-protein signalling 1; RGS1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5996
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.57 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: Q08116
• Gene Symbols: RGS1
• Immunogen: Recombinant protein encompassing a sequence within the center region of human RGS1. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG