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Invitrogen™ RGR Polyclonal Antibody
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Product Code. 16637474
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Quantity:
100 μL
Unit Size:
100µL
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16637474 100 μL 100µL
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Product Code. 16637474 Supplier Invitrogen™ Supplier No. PA5100993

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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total RGR.

This gene encodes a putative retinal G-protein coupled receptor. The gene is a member of the opsin subfamily of the 7 transmembrane, G-protein coupled receptor 1 family. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. The protein acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal. The reverse isomerization occurs with rhodopsin in retinal photoreceptor cells. The protein is exclusively expressed in tissue adjacent to retinal photoreceptor cells, the retinal pigment epithelium and Mueller cells. This gene may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP, respectively). Alternative splicing results in multiple transcript variants encoding different isoforms.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RGR
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene RGR
Gene Accession No. P47804
Gene Alias retinal G protein coupled receptor; Rgr; RGR opsin; RGR-opsin; RP44; RPE retinal G-protein coupled receptor; RPE-retinal G protein-coupled receptor
Gene Symbols RGR
Host Species Rabbit
Immunogen A synthesized peptide derived from human RGR(Accession P47804), corresponding to amino acid residues S130-M180.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5995
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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