Invitrogen™ RGMB Polyclonal Antibody

Goat Polyclonal Antibody

Brand:  Invitrogen™ PA547520

Product Code. 15548012

Description

In direct ELISAs and Western blots, approximately 50% cross-reactivity with recombinant mouse RGM-B is observed and less than 1% cross-reactivity with recombinant human (rh) RGM-A and rhRGM-C is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

Repulsive Guidance Molecule B (RGMB) is primarily expressed in the central nervous system. RGM A and B both appear at every level of the developing neural axis, where they colocalize to a large extent in the mantle layer, although only RGMA appears in the neuroepithelium, and only RGMB in the peripheral nervous system. During development, both RGMA and B appear also in lung and in limb cartilage, while RGMB has additional expression domains in pancreas.

Specifications

• Antigen: RGMB
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RGMB
• Gene Alias: 1110059F19Rik; DRAGON; DRG11-responsive axonal guidance and outgrowth of neurite; repulsive guidance molecule B; repulsive guidance molecule family member B; RGM domain family member B; RGM domain family, member B; RGMB
• Host Species: Goat
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 285704
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Flow Cytometry, Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: Q6NW40
• Gene Symbols: RGMB
• Immunogen: Mouse myeloma cell line NS0-derived recombinant human RGM-B isoform 1 Gly46-SerSer411.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG