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RG108, MedChemExpress

Product Code. 16495788
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Product Code. 16495788 Supplier Medchem Express Supplier No. HY13642

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Description

MedChemExpress RG108 (N-Phthalyl-L-tryptophan) is a non-nucleoside DNA methyltransferases (DNMTs) inhibitor (IC50=115 nM) that blocks the DNMTs active site. RG108 (N-Phthalyl-L-tryptophan) causes demethylation and reactivation of tumor suppressor genes, but it does not affect the methylation of centromeric satellite sequences.

RG108 (N-Phthalyl-L-tryptophan) is a non-nucleoside DNA methyltransferases (DNMTs) inhibitor (IC50=115 nM) that blocks the DNMTs active site. RG108 (N-Phthalyl-L-tryptophan) causes demethylation and reactivation of tumor suppressor genes, but it does not affect the methylation of centromeric satellite sequences.

Specifications

Chemical Name or Material RG108
Physical Form Powder
CAS 48208-26-0
Color Yellow
Quantity 10 mg
Purity Grade Notes Research
Molecular Formula C19H14N2O4
For Use With (Application) Cancer-programmed cell death
Synonym N-Phthalyl-L-tryptophan
Solubility Information DMSO : 100 mg/mL (299.11 mM; Need ultrasonic) ∣H2O : < 0.1 mg/mL (insoluble)
SMILES O=C(N1[C@H](C(O)=O)CC2=CNC3=C2C=CC=C3)C4=CC=CC=C4C1=O
Molecular Weight (g/mol) 334.33
Formula Weight 334.33
Percent Purity 99.51%
Grade Research
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Research purposes only

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