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STEMCELL Technologies RG108

Product Code. 17140042
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Quantity:
5 mg
10 mg
Unit Size:
10mg
5mg
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Product Code. 17140042

Brand: STEMCELL Technologies 72212

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This item is not returnable. View return policy

Description

Epigenetic modifier; Inhibits DNA methyltransferase (DNMT)

  • RG108 is an epigenetic modifier that inhibits DNA methyltransferase (IC50 = 115 nM)
  • RG108 is a non-nucleoside inhibitor that acts by direct binding to the methyltransferase enzyme whereby it blocks the enzyme active site
  • (Brueckner et al.), Stresemann et al.)
  • Enhances reprogramming efficiency of human and mouse somatic cells to induced pluripotent stem (iPS) cells (Mali et al.), Pasha et al.), Shi et al.)

Specifications

CAS 48208-26-0
Synonym N-Phthalyl-L-Tryptophan
Quantity 5 mg
Molecular Formula C19H14N2O4
Purity ≥98%
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