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RG-12525, MedChemExpress

Product Code. 16496217
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Quantity:
5 mg
10 mg
Unit Size:
10mg
5mg
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Product Code. 16496217

Brand: Medchem Express HY101676

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Description

MedChemExpress RG-12525 is a a specific, competitive and orally effective antagonist of the peptidoleukotrienes, LTC4, LTD4 and LTE4, inhibiting LTC4-, LTD4- and LTE4-inducd guinea pig parenchymal strips contractions, with IC50s of 2.6 nM, 2.5 nM and 7 nM, respectively; RG-12525 is also a peroxisome proliferator-activated receptor gamma (PPAR-gamma) agonist with IC50 of appr 60 nM and a potent inhibitor of CYP3A4, with a Ki value of 0.5 μM.

RG-12525 is a a specific, competitive and orally effective antagonist of the peptidoleukotrienes, LTC4, LTD4 and LTE4, inhibiting LTC4-, LTD4- and LTE4-inducd guinea pig parenchymal strips contractions, with IC50s of 2.6 nM, 2.5 nM and 7 nM, respectively

Specifications

Chemical Name or Material RG-12525
CAS 120128-20-3
Color Yellow
Purity Grade Notes Research
Molecular Formula C25H21N5O2
Quantity 5 mg
Synonym NID 525
Solubility Information DMSO : 25 mg/mL (59.04 mM; Need ultrasonic)
SMILES C1(COC2=CC=C(OCC3=CC=CC=C3CC4=NN=NN4)C=C2)=NC5=CC=CC=C5C=C1
Molecular Weight (g/mol) 423.47
Formula Weight 423.47
Percent Purity 98.39%
Grade Research
Physical Form Solid
For Use With (Application) Metabolism-sugar/lipid metabolism
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Research purposes only

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