Invitrogen™ RFC3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA527942

Product Code. 13452057

Description

Recommended positive controls: HeLa. Predicted reactivity: Mouse (96%), Rat (96%), Zebrafish (83%), Xenopus laevis (87%), Pig (97%), Chicken (88%), Rhesus Monkey (100%), Bovine (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 38 kD subunit. This subunit is essential for the interaction between the 140 kD subunit and the core complex that consists of the 36, 37, and 40 kD subunits. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Specifications

• Antigen: RFC3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RFC3
• Gene Alias: 2810416I22Rik; 38kDa; A1 38 kDa subunit; Activator 1 38 kDa subunit; activator 1 subunit 3; AU022547; DNA-binding; MGC5276; Polymorphism; Recc3; replication factor C (activator 1) 3; replication factor C (activator 1) 3, 38kDa; replication factor C 3; replication factor C 38 kDa subunit; Replication factor C subunit 3; replication factor C, 38 kDa; RF-C 38 kDa subunit; RFC, 38 kD subunit; RFC3; RFC38
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5983
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.43 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P40938
• Gene Symbols: RFC3
• Immunogen: Recombinant protein encompassing a sequence within the center region of human RFC3. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG