Invitrogen™ RFC3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA575437

Product Code. 15931965

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 38 kD subunit. This subunit is essential for the interaction between the 140 kD subunit and the core complex that consists of the 36, 37, and 40 kD subunits. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Specifications

• Antigen: RFC3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RFC3
• Gene Alias: 2810416I22Rik; 38kDa; A1 38 kDa subunit; Activator 1 38 kDa subunit; activator 1 subunit 3; AU022547; DNA-binding; MGC5276; Polymorphism; Recc3; replication factor C (activator 1) 3; replication factor C (activator 1) 3, 38kDa; replication factor C 3; replication factor C 38 kDa subunit; Replication factor C subunit 3; replication factor C, 38 kDa; RF-C 38 kDa subunit; RFC, 38 kD subunit; RFC3; RFC38
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 288414, 5983, 69263
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P40938, Q8R323
• Gene Symbols: RFC3
• Immunogen: Synthetic peptide corresponding to amino acids 200-250 of Human RFC3.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG