Invitrogen™ RFC2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5104384

Product Code. 16650835

Description

Antibody detects endogenous levels of total RFC2.

This gene encodes a member of the activator 1 small subunits family. The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins, proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). Replication factor C, also called activator 1, is a protein complex consisting of five distinct subunits. This gene encodes the 40 kD subunit, which has been shown to be responsible for binding ATP and may help promote cell survival. Disruption of this gene is associated with Williams syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene of this gene has been defined on chromosome 2.

Specifications

• Antigen: RFC2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RFC2
• Gene Alias: 2610008M13Rik; 40kDa; A1 40 kDa subunit; Activator 1 40 kDa subunit; activator 1 subunit 2; Activator 1 subunit C2; AI326953; MGC3665; Recc2; replication factor C (activator 1) 2; replication factor C (activator 1) 2, 40kDa; replication factor C 40 kDa subunit; Replication factor C subunit 2; replication factor C, 40 kDa; RF-C 40 kDa subunit; RFC2; RFC40
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 116468, 19718, 5982
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P35250, Q641W4, Q9WUK4
• Gene Symbols: RFC2
• Immunogen: A synthesized peptide derived from human RFC2(Accession P35250), corresponding to amino acid residues K208-P258.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG