Retinol Binding Protein RBP Antibody (SPM442), DyLight 550, Novus Biologicals™

Mouse Monoclonal Antibody

Brand:  Novus Biologicals NBP2-34410R

Product Code. 18181412

Description

Retinol Binding Protein RBP Monoclonal specifically detects Retinol Binding Protein RBP in Human, Mouse, Rat, Goat, Monkey, Rabbit samples. It is validated for Western Blot, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

Specifications

• Antigen: RBP4/Retinol-Binding Protein 4
• Classification: Monoclonal
• Conjugate: DyLight 550
• Gene Alias: interstitial, Plasma retinol-binding protein, retinol binding protein 4, plasma, retinol-binding protein 4, plasma
• Host Species: Mouse
• Molecular Weight of Antigen: 23 kDa
• Quantity: 0.1 mL
• Research Discipline: Cancer, Diabetes Research, Lipid and Metabolism
• Gene ID (Entrez): 5950
• Target Species: Human, Mouse, Rat, Goat, Primate, Rabbit
• Form: Purified

• Applications: Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
• Clone: SPM442
• Dilution: Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
• Gene Symbols: RBP4
• Immunogen: Retinol binding protein purified from human plasma
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: Recognizes a protein of 21kDa-25kDa, identified as retinol binding protein (RBP). Its epitope localizes between aa 74-182 of human RBP. This monoclonal antibody recognizes reduced and carboxy-methylated RBP (RCM-RBP) as well as the circulatory RBP but not the native RBP, thereby suggesting that its epitope becomes accessible either on unfolding or upon binding of RBP to transthyretin (prealbumin). RBP is responsible for distributing retinol from the retinoid stores in the liver to the various target tissues. Once secreted into the blood with bound retinol, the vitamin carrier circulates complexed with transthyretin prior to vitamin delivery at the plasma membrane through a receptor-mediated mechanism.
• Content And Storage: Store at 4C in the dark.
• Isotype: IgG1 κ

For Research Use Only