Retinol, 95%, synthetic

Product Code.	Quantity	unitSize
15434529	1 g	1g
15444529	5 g	5g

Product Code. 15434529 Supplier Thermo Scientific Alfa Aesar Supplier No. J62079.03

Description

All-trans-retinol, Vitamin A, retinol, CAS # 68-26-8, is a fat-soluble vitamin that binds retinoid receptors within cells. | CAS: 68-26-8 | C20H30O | 286.46 g/mol

It induces cell differentiation and apoptosis of some cancer cell types and inhibiting carcinogenesis. It plays an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune response. It acts as a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR) that act as transcription factors to regulate the growth and differentiation of normal and malignant cells.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General description
• All-trans-retinol, commonly known as Vitamin A, is a fat-soluble essential nutrient
• All-trans-retinol is involved in hormonal signaling via the retinoid receptors
• It is an important regulator of cell division and apoptosis
• Deficiency can lead to vision, bone, immune, and skin disorders

Applications
• Suitable for research on cell differentiation, embryonic development, immunology and more
• Laboratory grade quality, for research use only

Specifications

Chemical Identifiers

• CAS: 68-26-8
• Molecular Formula: C20H30O
• MDL Number: MFCD00001552
• InChI Key: FPIPGXGPPPQFEQ-OVSJKPMPSA-N
• PubChem CID: 445354
• ChEBI: CHEBI:17336

• Color: White to Yellow
• Quantity: 1 g
• Beilstein: 403040
• Sensitivity: Light and moisture sensitive
• Merck Index: 14,10013
• Synonym: retinol, vitamin a, all-trans-retinol, vitamin a1, alphalin, axerophthol, vitamin a alcohol, oleovitamin a, chocola a, alphasterol
• Solubility Information: Practically insoluble in water or glycerol; soluble in absolute alcohol, methanol, chloroform,ether,fats and oils.
• SMILES: CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CCO)C)C
• IUPAC Name: (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraen-1-ol
• Molecular Weight (g/mol): 286.459
• Formula Weight: 286.46
• Percent Purity: 95%
• Physical Form: Crystalline Solid
• Chemical Name or Material: Retinol, synthetic

Seguridad y manipulación

Nombre del producto

• Retinol

Palabra de advertencia

• Warning

Clasificación

• Acute toxicity Category 4
• Serious eye damage/eye irritation Category 2
• Reproductive toxicity Category 2
• Skin corrosion/irritation Category 2

Indicaciones de peligro

• H302-Harmful if swallowed.
• H315-Causes skin irritation.
• H319-Causes serious eye irritation.
• H361d-Suspected of damaging the unborn child.

Consejos de prudencia

• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
• P302+P352-IF ON SKIN: Wash with plenty of water/soap.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P312-Call a POISON CENTER/doctor/if you feel unwell.

Otros peligros

• MIXTURE LIST-Contain: Vitamin A

RUO – Research Use Only