Retinoic acid, MedChemExpress

Product Code. 16471429

Brand: Medchem Express HY14649

Description

MedChemExpress Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha.

Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha.

Specifications

• Chemical Name or Material: Retinoic acid
• CAS: 302-79-4
• Color: Yellow
• Purity Grade Notes: Research
• Molecular Formula: C₂₀H₂₈O₂
• Quantity: 1 g
• Synonym: Vitamin A acid all-trans-Retinoic acid ATRA
• Solubility Information: DMSO : 50 mg/mL (166.42 mM; ultrasonic and warming and heat to 60°C)
• SMILES: CC1(C)C(/C=C/C(C)=C/C=C/C(C)=C/C(O)=O)=C(C)CCC1
• Molecular Weight (g/mol): 300.44
• Formula Weight: 300.44
• Percent Purity: 96.11%
• Grade: Research
• Physical Form: Solid
• For Use With (Application): Cancer-programmed cell death

Research purposes only