Retinoic acid, 97%

Product Code. 11465290

Brand: Thermo Scientific Alfa Aesar 044540.02

Description

All-trans-retinol, Vitamin A, retinol is a fat-soluble vitamin that binds retinoid receptors within cells. | CAS: 302-79-4 | C20H28O2 | 300.44 g/mol

Retinoic acid is used in dermatology drugs. It is used in the treatment of psoriasis, ichthyosis, follicular keratosis, acne, lichen planus, verrucous epidermal nevus and lichen psoriasis. It is also employed in promoting the proliferation and differentiation of epithelial cells. In addition to this, it exhibits some preventive effect on skin cancer.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General description

• All-trans-retinol, commonly known as Vitamin A, is a fat-soluble essential nutrient

• All-trans-retinol is involved in hormonal signaling via the retinoid receptors

• It is an important regulator of cell division and apoptosis

• Deficiency can lead to vision, bone, immune, and skin disorders

Applications

• Suitable for research on cell differentiation, embryonic development, immunology and more

• Laboratory grade quality, for research use only

Tekniske data

Kemiske identifikatorer

• CAS: 302-79-4
• Molecular Formula: C20H28O2
• Molecular Weight (g/mol): 300.44
• MDL Number: MFCD00001551
• InChI Key: SHGAZHPCJJPHSC-YCNIQYBTSA-N
• Synonym: retinoic acid, tretinoin, vitamin a acid, all-trans-retinoic acid, trans-retinoic acid, renova, airol, retin-a, vesanoid, atra
• PubChem CID: 444795
• ChEBI: CHEBI:15367
• SMILES: C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(O)=O

• Melting Point: 180°C to 182°C
• Quantity: 0.5 g
• Beilstein: 2057223
• Sensitivity: Light sensitive
• Merck Index: 14,8165
• Solubility Information: Soluble in ethanol,acetate,dimethyl formamide,dimethyl sulfoxide,chloroform,methanol,acetone and dichloromethane. Insoluble in water and ether.
• IUPAC Name: (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoic acid
• Formula Weight: 300.44
• Percent Purity: 98%
• Physical Form: Crystalline
• Chemical Name or Material: Retinoic acid

Sikkerhed og håndtering

Produktidentifikator

• Retinoic acid

Signalord

• Warning

Farekategori

• Acute toxicity Category 4
• Serious eye damage/eye irritation Category 2
• Reproductive toxicity Category 2
• Skin corrosion/irritation Category 2
• Specific target organ toxicity Category 3

Faresætning

• H302-Harmful if swallowed.
• H312-Harmful in contact with skin.
• H315-Causes skin irritation.
• H319-Causes serious eye irritation.
• H335-May cause respiratory irritation.
• H361d-Suspected of damaging the unborn child.

Sikkerhedssætning

• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
• P302+P352-IF ON SKIN: Wash with plenty of water/soap.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P312-Call a POISON CENTER/doctor/if you feel unwell.

Supplerende oplysninger

• MIXTURE LIST-Contains : all-trans-Retinoic acid

SDS

RUO – Research Use Only