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  6. Retinoblastoma (Rb) (Phospho-specific Serine) Ab-7, Mouse Monoclonal Antibody,Lab Vision™ Epredia™

Retinoblastoma (Rb) (Phospho-specific Serine) Ab-7, Mouse Monoclonal Antibody,Lab Vision™ Epredia™

Product Code. 12680397 Shop All Epredia Products
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Quantity:
100 μL
200 μL
500 μL
Concentration:
1mg/mL
200μg/mL
Unit Size:
100µL
200µL
500µL
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Product Code. Quantity Concentration unitSize
12680397 500 μL 200μg/mL 500µL
12650397 100 μL 200μg/mL 100µL
12670397 100 μL 1mg/mL 100µL
12690397 200 μL 1mg/mL 200µL
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Product Code. 12680397 Supplier Epredia Supplier No. MS1883P1

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This item is not returnable. View return policy

Description

Provide accurate, reproducible results with the Epredia™ Retinoblastoma (Rb) (Phospho-specific Serine) Ab-7, Mouse Monoclonal Antibody.

Rb is a tumor suppressor nuclear phosphoprotein capable of binding to DNA. It is phosphorylated on serine and threonine, but not on tyrosine residues. It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus-16 E. Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth. Aberrations in the RB gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia. Phosphorylation of Rb at S608 depends on CDK4.

Host Species: Mouse

Clone: 51B7

Isotype: IgG1

Species Reactivity: Human and Mouse. Others not known.

Molecular Weight: 105kDa

Positive Control: Ls174T cells

Cellular Localization: Nuclear Ab-7 reacts with human and mouse protein phosphorylated on S608. It does not react with nonphosphorylate Rb or Rb phosphorylated at other sites.

Recommended for:

  • Western Blotting

Note:

USA: RUO; Int'l: RUO

TRUSTED_SUSTAINABILITY

Specifications

Antigen Retinoblastoma (Rb) (Phospho-specific Serine) Ab-7
Applications Western Blot
Classification Monoclonal
Clone 51B7
Concentration 200μg/mL
Conjugate Unconjugated
Host Species Mouse
Quantity 500 μL
Regulatory Status RUO
Research Discipline Cancer and Tumor Biology
Primary or Secondary Primary
Target Species Human, Mouse
Form Concentrated
Isotype IgG1
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