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Eurofins DiscoverX Ret Protein, Active
Description
The RET (rearranged during transfection) receptor tyrosine kinase is a classic example of phenotype heterogeneity. Gain-of-function mutations of RET are associated with human cancer and multiple endocrine neoplasia type 2 (MEN 2A, MEN 2B, etc.) Loss-of-function mutations of RET cause Hirschspung disease or colonic aganglionosis).
GenBank NM_000323
Specifications
Specifications
| Formulation | mg/mL of enzyme in 50 mM Tris/HCl pH 7.5, 150 mM NaCl, 0.1 mM EGTA, 0.03% Brij-35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution. |
| Molecular Weight (g/mol) | 79.2 kDa |
| Quantity | 10 μg |
| Species | Human |
| Recombinant | Recombinant |
| Protein Tag | N-terminal GST |
| Expression System | Recombinant enzyme expressed in Sf21 insect cells |
| Protein Form | Truncated |
| Purity or Quality Grade | ≥58% |
| Protein | Ret, active |
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