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RET Polyclonal Antibody, Invitrogen™

Product Code. 15545431
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Quantity:
100 μg
Unit Size:
100µg
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Product Code. Quantity unitSize
15545431 100 μg 100µg
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Product Code. 15545431 Supplier Invitrogen Supplier No. PA538509

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Beskrivelse

Rabbit Polyclonal Antibody

RET is a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases which are cell-surface molecules that transduce signals for cell growth and differentiation. RET plays a crucial role in neural crest development, can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in the RET gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for the RET gene. Additional transcript variants have been described for RET but their biological validity has not been confirmed.
TRUSTED_SUSTAINABILITY

Tekniske data

Antigen Ret
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene RET
Gene Accession No. P07949, P35546, G3V9H8
Gene Alias C-ret, EC 2.7.10.1, Proto-oncogene ret precursor, kinase Ret
Gene Symbols RET
Host Species Rabbit
Immunogen A synthetic non-phosphopeptide derived from human Ret around the phosphorylation site of Tyr905 (D-S-YP-V-K)
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19713, 24716, 5979
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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