Resatorvid, MedChemExpress

Product Code.	Quantity	unitSize
16465296	100 mg	100mg
16417127	5 mg	5mg
16404408	10 mg	10mg
16400727	50 mg	50mg

Product Code. 16465296 Supplier Medchem Express Supplier No. HY11109

Description

MedChemExpress Resatorvid (TAK-242) is a selective Toll-like receptor 4 (TLR4) inhibitor. Resatorvid inhibits NO, TNF-α and IL-6 production with IC50s of 1.8 nM, 1.9 nM and 1.3 nM, respectively. Resatorvid downregulates expression of TLR4 downstream signaling molecules MyD88 and TRIF. Resatorvid inhibits autophagy and plays pivotal role in various inflammatory diseases.

Resatorvid (TAK-242) is a selective Toll-like receptor 4 (TLR4) inhibitor. Resatorvid inhibits NO, TNF-α and IL-6 production with IC50s of 1.8 nM, 1.9 nM and 1.3 nM, respectively. Resatorvid downregulates expression of TLR4 downstream signaling molecules MyD88 and TRIF. Resatorvid inhibits autophagy and plays pivotal role in various inflammatory diseases.

Specifications

• Chemical Name or Material: Resatorvid
• CAS: 243984-11-4
• Color: Yellow
• Purity Grade Notes: Research
• Molecular Formula: C₁₅H₁₇ClFNO₄S
• Quantity: 100 mg
• Synonym: TAK-242 CLI-095
• Solubility Information: DMSO : 100 mg/mL (276.38 mM; Need ultrasonic)
• SMILES: O=S([C@H]1C(C(OCC)=O)=CCCC1)(NC2=CC=C(C=C2Cl)F)=O
• Molecular Weight (g/mol): 361.82
• Formula Weight: 361.82
• Percent Purity: 98.04%
• Grade: Research
• Physical Form: Solid
• For Use With (Application): COVID-19-immunoregulation

Research purposes only