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  6. Invitrogen™ REPIN1 Recombinant Rabbit Monoclonal Antibody (2X2E9)

Invitrogen™ REPIN1 Recombinant Rabbit Monoclonal Antibody (2X2E9)

Product Code. 30284436
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100 μL
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20µL
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30284436 20 μL 20µL
30284131 100 μL 100µL
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Product Code. 30284436 Supplier Invitrogen™ Supplier No. MA557991

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Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: SCDDCGRSFR LERFLRAHQR QHTGERPFTC AECGKNFGKK THLVAHSRVH SGERPFACEE CGRRFSQGSH LAAHRRDHAP DRPFVCPDCG KAFRHKPYLA AHRRIHTGEK PYVCPDCGKA FSQKSNLVSH RRIHTGERPY ACPDCDRSFS QKSNLITHRK SHIRDGAFCC AICGQTFDDE ERLLAHQKKH DV.

Replication initiator 1 (REPIN1) is a gene encoding a zinc-finger protein that plays a critical role in various metabolic processes. Located on chromosome 7 in humans, REPIN1 is prominently expressed in liver and adipose tissues. It is associated with the regulation of body weight and triglyceride levels, as evidenced by its locus within a quantitative trait locus (QTL) related to these metabolic traits. The REPIN1 protein is involved in enhancing DNA bending, which is crucial for replication initiation. Studies have shown that deleting REPIN1 in the liver can lead to improved insulin sensitivity and altered lipid metabolism, with secondary effects on adipose tissue. Additionally, REPIN1 is implicated in iron metabolism and apoptosis regulation, further underscoring its multifaceted role in cellular processes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen REPIN1
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone 2X2E9
Concentration 1.01 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene REPIN1
Gene Accession No. Q9BWE0
Gene Alias 60 kDa origin-specific DNA-binding protein; 60 kDa replication initiation region protein; AP4; ATT-binding protein; DHFR oribeta-binding protein RIP60; H_DJ0584D14.12; REPIN1; replication initiation region protein (60kD); replication initiator 1; RIP60; Zfp464; Zinc finger protein 464; zinc finger protein 464 (RIP60); zinc finger protein AP4; ZNF464
Gene Symbols REPIN1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 376-567 of human REPIN1 (NP_037532.2).
Purification Method Protein A
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 29803
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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