Remoxipride hydrochloride, Tocris Bioscience™

Description

Dopamine D2 receptor antagonist showing selectivity over D3 and D4 receptors (Ki values are ∽ 300, ∽ 1600, and ∽ 2800 nM for D2, D3 and D4 receptors respectively). Exhibits antipsychotic activity in vivo with no extrapyramidal side effects. 50-fold more potent than sulpiride in antagonising the effects of apomorphine in the rat.

Chemical Identifiers

• CAS: 73220-03-8
• Molecular Weight (g/mol): 407.733
• Synonym: remoxipride hydrochloride, roxiam, remoxipride hcl, a 33547 hydrochloride, unii-qs4s72u30k, s-remoxipride, remoxipride hydrochloride anhydrous, s---2-3-bromo-2,6-dimethoxybenzamido methyl-1-ethylpyrrolidine hydrochloride, s---3-bromo-2,6-dimethoxy-n-1-ethyl-2-pyrrolidinylmethyl benzamide hydrochloride, benzamide, 3-bromo-2,6-dimethoxy-n-1-ethyl-2-pyrrolidinylmethyl-, hydrochloride, s--
• IUPAC Name: 3-bromo-N-[[(2S)-1-ethylpyrrolidin-2-yl]methyl]-2,6-dimethoxybenzamide;hydrochloride

• Molecular Formula: C16H24BrClN2O3
• InChI Key: WCPXLMIPGMFZMY-MERQFXBCSA-N
• PubChem CID: 15565709
• SMILES: CCN1CCCC1CNC(=O)C2=C(C=CC(=C2OC)Br)OC.Cl

Specifications

• CAS: 73220-03-8
• Synonym: remoxipride hydrochloride, roxiam, remoxipride hcl, a 33547 hydrochloride, unii-qs4s72u30k, s-remoxipride, remoxipride hydrochloride anhydrous, s---2-3-bromo-2,6-dimethoxybenzamido methyl-1-ethylpyrrolidine hydrochloride, s---3-bromo-2,6-dimethoxy-n-1-ethyl-2-pyrrolidinylmethyl benzamide hydrochloride, benzamide, 3-bromo-2,6-dimethoxy-n-1-ethyl-2-pyrrolidinylmethyl-, hydrochloride, s--
• SMILES: CCN1CCCC1CNC(=O)C2=C(C=CC(=C2OC)Br)OC.Cl
• Molecular Weight (g/mol): 407.733
• Formula Weight: 407.73
• Chemical Name or Material: Remoxipride hydrochloride

• Molecular Formula: C16H24BrClN2O3
• InChI Key: WCPXLMIPGMFZMY-MERQFXBCSA-N
• IUPAC Name: 3-bromo-N-[[(2S)-1-ethylpyrrolidin-2-yl]methyl]-2,6-dimethoxybenzamide;hydrochloride
• PubChem CID: 15565709
• Percent Purity: >98%

Safety and Handling

Recommended Storage : Store at Room Temperature