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  6. Invitrogen™ Relaxin 3 Monoclonal Antibody (D10)

Invitrogen™ Relaxin 3 Monoclonal Antibody (D10)
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Product Code. 17768313
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200 μL
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20µL
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Product Code. Quantity unitSize
17768313 200 μL 200µL
17654066 20 μL 20µL
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Product Code. 17768313 Supplier Invitrogen™ Supplier No. MA541667

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Description

Mouse Monoclonal Antibody

Relaxin 3 Monoclonal Antibody for Western Blot, ICC/IF, IHC (P)

Relaxin 3 is part of the Relaxin-like peptide family that plays an important neuropeptide signaling role. Relaxin 3 is a ligand for two structurally related G protein-coupled receptors, human Relaxin receptor 3 and Relaxin receptor 4. The greatest levels of Relaxin 3 expression occur in the brain, specifically in the pons/medulla, with highest levels in the pars ventromedialis of the dorsal tegmental nucleus and with lower levels in the hippocampus and olfactory regions. Significant expression is also observed in the spleen, thymus, lung and ovary. Relaxin 3 inhibits Forskolin-stimulated cAMP accumulation in a dose-dependent manner in cells that express Relaxin receptor 3. Acute and repeated administration of Relaxin 3 causes a decrease in levels of the plasma thyroid stimulating hormone, suggesting that Relaxin 3 may play a role in long-term control of food intake.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Relaxin 3
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone D10
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
Gene RLN3
Gene Accession No. Q8BFS3, Q8WXF3
Gene Alias H3; insl7; insulin-like 7; insulin-like peptide 7; Insulin-like peptide INSL7; M3; PRO20213; Prorelaxin H3; prorelaxin M3; relaxin 3; relaxin-3; Relaxin-3 A chain; Relaxin-3 B chain; RLN3; RXN3; UNQ6188; UNQ6188/PRO20213; ZINS4
Gene Symbols RLN3
Host Species Mouse
Immunogen Recombinant protein Relaxin 3. The antigen corresponds to amino acid range 1-140 of the target protein.
Purification Method Protein A/G
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 117579, 266997
Target Species Human, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2b κ
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