Invitrogen™ Relaxin 2 Monoclonal Antibody (349102)

Rat Monoclonal Antibody

Brand:  Invitrogen™ MA524088

Product Code. 15513782

Description

This antibody detects both the pro and mature forms of human Relaxin-2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) Relaxin-1 or rhRelaxin-3 is observed. Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 μg of the antibody by the LAL method.

Relaxin 1 (also referred to as Relaxin or RLXH1) is a peptide hormone produced by the corpora lutea of the ovary during pregnancy in many mammalian species, including human. The secretion of the hormone into the blood stream just before parturition results in a marked softening and lengthening of the pubic symphysis and a softening of the cervix, which facilitates the birth process. By inhibiting uterine contractions, Relaxin 1 may influence the timing of parturition. Like insulin, Relaxin 1 consists of two peptide chains, A and B, covalently linked by disulfide bonds. By further analogy to insulin, the two peptides are synthesized as a single-chain precursor polypeptide with the B chain at the amino-terminus. The gene that encodes the human Relaxin 1 protein maps to chromosome 9. Relaxin 2, a related protein, is selectively expressed in the ovary during pregnancy. The gene that encodes the human Relaxin 2 protein also maps to chromosome 9.

Specifications

• Antigen: Relaxin 2
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: P04090
• Gene Symbols: RLN2
• Immunogen: E. coli-derived recombinant human Relaxin-2 Val23-Cys185.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Neutralization, Western Blot
• Clone: 349102
• Conjugate: Unconjugated
• Gene: RLN2
• Gene Alias: bA12D24.1.1; bA12D24.1.2; H2; H2-preprorelaxin; H2-RLX; Prorelaxin H2; relaxin 2; Relaxin A chain; Relaxin B chain; relaxin H2; relaxin, ovarian, of pregnancy; RLN2; RLX H2-RLX; RLXH2
• Host Species: Rat
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 6019
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized