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Regorafenib Hydrochloride, MedChemExpress

Product Code. 16445638
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Product Code. 16445638

Brand: Medchem Express HY13308

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Description

MedChemExpress Regorafenib Hydrochloride (BAY 73-4506 hydrochloride) is a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1 with IC50s of 13/4.2/46, 22, 7, 1.5 and 2.5 nM, respectively.

Regorafenib Hydrochloride (BAY 73-4506 hydrochloride) is a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1 with IC50s of 13/4.2/46, 22, 7, 1.5 and 2.5 nM, respectively.

Specifications

Chemical Name or Material Regorafenib Hydrochloride
CAS 835621-07-3
Color Off-White
Purity Grade Notes Research
Molecular Formula C21H16Cl2F4N4O3
Quantity 10 mg
Synonym BAY 73-4506 hydrochloride
Solubility Information DMSO : ≥ 5.6 mg/mL (10.78 mM) ∣H2O : < 0.1 mg/mL (insoluble)
SMILES ClC1=C(C(F)(F)F)C=C(NC(NC2=C(F)C=C(OC3=CC=NC(C(NC)=O)=C3)C=C2)=O)C=C1.Cl
Molecular Weight (g/mol) 519.28
Formula Weight 519.28
Percent Purity 98.0%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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