enQuireBio™ Recombinant Rat Leptin tA Protein

A cDNA sequence encoding the Leptin tA was constructed and used to recombinantly synthesize the protein.

Brand:  enQuireBio™ QP10765-5ug

Product Code. 15965098

Specifications

• Name: Leptin tA Protein
• Regulatory Status: Research Use Only
• Biological Activity: Leptin Antagonist Triple Mutant Rat Recombinant half-life in circulation after SC injection was over 20 hours. Leptin Antagonist Triple Mutant Rat Recombinant is capable of inhibiting leptin-induced proliferation of BAF/3 cells stably transfected with the long form of human leptin receptor. Leptin Antagonist Triple Mutant Rat Recombinant in vitro activity is 5-6 fold lower than the non-pegylated antagonist, though in vivo it has profound weight gain effect (as compared to the non-pegylated antagonist), resulting mainly from increased food intake.
• Cross Reactivity: Rat
• Protein Tag: Untagged
• Purity or Quality Grade: Greater than 99.0% as determined by:(a) Gel filtration analysis. (b) Analysis by SDS-PAGE.

• Quantity: 5 μg
• Endotoxin Concentration: < 1.0 EU per ug protein as determined by the LAL method.
• Product Type: Recombinant Protein
• Species: E. coli
• Buffer: The Rat Leptin triple antagonist was lyophilized from a concentrated (0.65 mg/ml) solution with 0.003mM NaHCO3.