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Description
TRAIL/TNFSF10 protein is fully biologically active when compared to standard. The ED50 as determined by a cytotoxicity assay using murine L929 cells is less than 0.5 ng/mL, corresponding to a specific activity of > 2.0 x 10^6 IU/mg in the presence of actinomycin D.
Specifications
Specifications
| For Use With (Application) | Bioactivity |
| Formulation | Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4, with 3 mM DTT. |
| Gene ID (Entrez) | 8743 |
| Molecular Weight (g/mol) | MolecularWeight-theroretical: 20.2 kDa |
| Quantity | 1000 μg |
| Storage Requirements | Store at -20°C to -70°C as supplied. After reconstitution, store at 2 to 8 C for 1 month and (at -20°C to -70°C for long term storage. Avoid repeated freeze/thaw cycles.) |
| Endotoxin Concentration | Less than 0.1 EU/μg of TRAIL/TNFSF10 as determined by LAL method. |
| Gene Alias | Apo-2 ligand, APO2L, Apo-2 Ltumor necrosis factor (ligand) family, member 10, APO2Ltumor necrosis factor apoptosis-inducing ligand splice variant delta, CD253, CD253 antigen, Protein TRAIL, TL2, TNF-related apoptosis-inducing ligand, TRAILTNF-related apoptosis inducing ligand TRAIL, tumor necrosis factor (ligand) superfamily, member 10, tumor necrosis factor ligand superfamily member 10 |
| Gene Symbol | TNFSF10 |
| Reconstitution | Recommended to centrifuge prior to opening. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL Apportion stock solutions into working aliquots and store (at <-20°C.) |
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