missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Recombinant Proteins
  4. 18349707

R&D Systems™ Recombinant Mouse CD47 Fc Chimera Protein

Product Code. 18349707
Change view
Click to view available options
Quantity:
50 μg
Unit Size:
50µg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Product Code. Quantity unitSize
18349707 50 μg 50µg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
This item is not returnable. View return policy
Product Code. 18349707 Supplier R&D Systems™ Supplier No. 1866CD050

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility. Applications: Bioactivity

Measured by its binding ability in a functional ELISA. When Recombinant Mouse SIRP alpha/CD172a Fc Chimera (Catalog # 7154-SA ) is coated at 2 μg/mL, Recombinant Mouse CD47 Fc Chimera binds with an apparent Kd <0.6 nM. Also measured by its ability to antagonize mouse red blood cell adhesion to immobilized Recombinant Mouse SIRP alpha/CD172a Fc Chimera (Catalog # 7154-SA ). The ED50 for this effect is 2.0-8.0 μg/mL. Optimal dilutions should be determined by each laboratory for each application.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number NP_034711
For Use With (Application) Bioactivity
Formulation Lyophilized from a 0.2 μm filtered solution in PBS.
Gene ID (Entrez) 961
Molecular Weight (g/mol) M.W. (Observed): 60-70 kDa, reducing conditions; M.W. (theoretical): 42.3 kDa (monomer)
Name CD47 Fc Chimera
Quantity 50 μg
Source Mouse myeloma cell line, NS0-derived mouse CD47 protein Mouse CD47 (Gln19-Pro158) (N-terminus) Accession # NP_034711 IEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)
Storage Requirements Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
Structural Form Disulfide-linked homodimer
Endotoxin Concentration <0.01 EU / 1 μg of the protein by the LAL method.
Gene Symbol Cd47
Conjugate Unconjugated
Recombinant Recombinant
Reconstitution Reconstitute at 200 μg/mL in PBS.
Purity or Quality Grade >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
Protein CD47
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.