R&D Systems™ Recombinant Human VSIG4 Short Isoform Fc Chimera Protein

Product Code. 18138220

Brand: R&D Systems™ 9817VS050

Description

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility.

Measured by its ability to inhibit anti-CD3 antibody induced IFN-gamma secretion by human peripheral blood mononuclear cells (PBMC). The ED50 for this effect is 1-5 μg/mL.

Specifications

• Accession Number: Q9Y279-3
• For Use With (Application): Bioactivity
• Formulation: Lyophilized from a 0.2 μm filtered solution in PBS.
• Gene ID (Entrez): 11326
• Molecular Weight (g/mol): M.W. (Observed): 55-65 kDa, reducing conditions; M.W. (theoretical): 46 kDa
• Name: CRIg, Ig superfamily protein, Protein Z39Ig, V-set and immunoglobulin domain containing 4, V-set and immunoglobulin domain-containing protein 4, Z39IG, Z39IGcomplement receptor of the immunoglobulin superfamily
• Quantity: 50 μg
• Source: Chinese Hamster Ovary cell line, CHO-derived human VSIG4 protein Human VSIG4 (Arg20-Pro189) (N-terminus) Accession # Q9Y279-3 IEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
• Endotoxin Concentration: <0.10 EU / 1 μg of the protein by the LAL method.
• Conjugate: Unconjugated
• Species: Human
• Reconstitution: Reconstitute at 200 μg/mL in PBS.
• Purity or Quality Grade: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
• Protein: VSIG4