R&D Systems™ Recombinant Human TLR3 Protein

Product Code.	Quantity	unitSize
18321708	50 μg	50µg

Product Code. 18321708 Supplier R&D Systems™ Supplier No. 1487TR050

Description

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility. Applications: Bioactivity

The Recombinant Human TLR3 Protein is derived from NS0. The Recombinant Human TLR3 Protein has been validated for the following applications: Bioactivity.

Specifications

• Formulation: Lyophilized from a 0.2μm filtered solution in PBS.
• Gene ID (Entrez): 7098
• Molecular Weight (g/mol): 79.2 kDa
• Name: TLR3
• Quantity: 50 μg
• Source: Mouse myeloma cell line,NS0-derived human TLR3 protein Lys27-Ser711,with a C-terminal 10-His tag
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70° C as supplied. 1 month, 2 to 8° C under sterile conditions after reconstitution. 3 months, -20 to -70° C under sterile conditions after reconstitution.
• Endotoxin Concentration: <0.10 EU per 1 μg of the protein by the LAL method.
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Activity: Measured by its ability to inhibit poly I:C induced IL-8 secretion by HEK293 human embryonic kidney cells transfected with TLR3. The ED50 for this effect is 5-10 μg/mL in the presence of 0.2 μg/mL of poly I:C.
• Purity or Quality Grade: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie Blue Staining.