R&D Systems™ Recombinant Human Noggin Fc Chimera Protein

Product Code.	Quantity	unitSize
18765937	500 μg	500µg
18385317	50 μg	50µg
18736066	100 μg	100µg

Product Code. 18765937 Supplier R&D Systems™ Supplier No. 3344NG500

Description

A New and Improved Noggin is Now Available! The new protein has ∼2 fold better activity, higher purity, and no tag! Earn double rewards for reviews

Measured by its ability to inhibit BMP-4-induced alkaline phosphatase production by ATDC5 mouse chondrogenic cells. The ED50 for this effect is 0.100-0.400 μg/mL in the presence of 30 ng/mL of Recombinant Human BMP-4 (Catalog number- 314-BP ).

Specifications

• Accession Number: Q13253
• For Use With (Application): Bioactivity
• Formulation: Lyophilized from a 0.2 μm filtered solution in PBS.
• Gene ID (Entrez): 9241
• Molecular Weight (g/mol): 49.6 kDa (monomer)
• Name: Noggin Fc Chimera
• Quantity: 500 μg
• Source: Mouse myeloma cell line, NS0-derived human Noggin protein, (N-terminus) Human Noggin (Gln28-Cys232) Accession Number-Q13253 IEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
• Structural Form: Disulfide-linked homodimer
• Gene Alias: NOG, noggin, SYM1, symphalangism 1 (proximal), synostoses (multiple) syndrome 1, SYNS1, SYNS1A
• Gene Symbol: NOG
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Reconstitution: Reconstitute at 100 μg/mL in sterile PBS.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS.
• Endotoxin Level: <0.10 EU per 1 μg of the protein by the LAL method.
• Purity or Quality Grade: 90%, by SDS-PAGE under reducing conditions and visualized by silver stain.