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R&D Systems™ Recombinant Human MAG/Siglec-4a Fc Chimera Protein

Product Code. 18737716
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50μg
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Product Code. 18737716

Brand: R&D Systems™ 8940MG050

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This item is not returnable. View return policy

Description

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility.

The Recombinant Human MAG/Siglec-4a Fc Chimera Protein is derived from HEK293. The Recombinant Human MAG/Siglec-4a Fc Chimera Protein has been validated for the following applications: Bioactivity.
TRUSTED_SUSTAINABILITY

Specifications

For Use With (Application) Bioactivity
Gene ID (Entrez) 4099
Molecular Weight (g/mol) Theoretical M.W.: 81kDa
Quantity 50μg
Source Human embryonic kidney cell,HEK293-derived human MAG/Siglec-4a protein, (N-terminus) Human MAG (Gly20-Pro516) Accession &Num; P20916 IEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)
Storage Requirements Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70° C as supplied. 1 month, 2 to 8° C under sterile conditions after reconstitution. 3 months, -20 to -70° C under sterile conditions after reconstitution.
Endotoxin Concentration <0.10 EU per 1μg of the protein by the LAL method.
Gene Alias GMAsialic acid binding Ig-like lectin 4A, myelin associated glycoprotein, myelin-associated glycoprotein, sialic acid-binding immunoglobulin-like lectin 4A, Siglec4a, SIGLEC-4A, S-MAG
Common Name MAG/Siglec-4a
Gene Symbol MAG
Biological Activity Measured by its ability to inhibit neurite outgrowth of dissociated E13 chick embryonic dorsal root ganglia (DRG) neurons. When immobilized as a 3μL droplet containing 200 ng on a nitrocellulose coated microplate, Recombinant Human MAG/Siglec-4a Fc Chimera is able to significantly inhibit neurite outgrowth.
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Expression System Human embryonic kidney cell, HEK293-derived Human MAG (Gly20-Pro516) Accession # P20916, N-terminus; IEGRMD; Human IgG1 (Pro100-Lys330), C-terminus
Purity or Quality Grade >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining
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