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R&D Systems™ Recombinant Human Integrin alpha V beta 6 Fc Protein, CF
Description
Measured by its binding ability in a functional ELISA. Recombinant Human Integrin alpha V beta 6 Fc Chimera (Catalog # 11649-AV) binds to Recombinant Human LAP (TGF-β1) (Catalog # 246-LP ) with an ED50 of 9.00-96.0 ng/mL.
Specifications
Specifications
| For Use With (Application) | Bioactivity |
| Formulation | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. |
| Gene ID (Entrez) | 3685 |
| Molecular Weight (g/mol) | MolecularWeight-observed: >190 kDa, under non-reducing conditions, MolecularWeight-theroretical: 133 kDa (Integrin alpha V) & 101 kDa (Integrin beta 6) |
| Quantity | 50 μg |
| Source | Human embryonic kidney cell, HEK293-derived human Integrin alpha V beta 6 protein Human ITGAV (Phe31-Val992) (N-terminus) Accession # AAA36808.1 IEGR Human IgG1 (Glu99-Lys330) (with modifications) Human ITGB6 (Gly22-Asn707) (N-terminus) Accession # P18564.2 HHPIEGR Human IgG1 (Glu99-Lys330) (with modifications) (C-terminus) |
| Storage Requirements | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution. |
| Endotoxin Concentration | <1.0 EU per 1 μg of the protein by the LAL method. |
| Gene Alias | CD51, integrin subunit alpha V, ITGAV, MSK8, VNRA, VTNR |
| Conjugate | Unconjugated |
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