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R&D Systems™ Recombinant Human IL-17A/F Heterodimer Biotin Protein

Product Code. 18772908
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25μg; Biotin
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Product Code. 18772908

Brand: R&D Systems™ BT5837025/CF

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356.00 GBP valid until 2025-12-16
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Description

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility.

The Recombinant Human IL-17A/F Heterodimer Biotin Protein is derived from CHO. The Recombinant Human IL-17A/F Heterodimer Biotin Protein has been validated for the following applications: Bioactivity.
TRUSTED_SUSTAINABILITY

Specifications

For Use With (Application) Bioactivity
Gene ID (Entrez) 3605
Molecular Weight (g/mol) Theoretical M.W.: 15kDa (unlabeled IL-17A), 15kDa (unlabeled IL-17F)
Quantity 25μg
Source Chinese Hamster Ovary cell line,CHO-derived human IL-17A/F Heterodimer protein, (N-terminus) Human IL-17A (Gly24-Ala155) Accession &Num; Q16552 Human IL-17F (Arg21-GLN163) Accession &Num; Q96PD4 (C-terminus)
Storage Requirements Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70° C as supplied. 1 month, 2 to 8° C under sterile conditions after reconstitution. 3 months, -20 to -70° C under sterile conditions after reconstitution.
Endotoxin Concentration <1.0 EU per 1μg of the protein by the LAL method.
Gene Alias CTLA8, CTLA8cytotoxic T-lymphocyte-associated serine esterase 8, Cytotoxic T-lymphocyte-associated antigen 8, Cytotoxic T-Lymphocyte-Associated Protein 8, IL17, IL-17, IL-17A, interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8), interleukin 17A, interleukin-17A
Common Name IL-17A/F Heterodimer
Biological Activity Measured by its ability to induce IL-6 secretion by NIH-3T3 mouse embryonic fibroblast cells. The ED50 for this effect is typically 0.4-2ng/mL.
Conjugate Biotin
Species Human
Recombinant Recombinant
Expression System Chinese Hamster Ovary cell line, CHO-derived Human IL-17A (Gly24-Ala155) Accession # Q16552, N-terminus; Human IL-17F (Arg21-GLN163) Accession # Q96PD4, C-terminus
Purity or Quality Grade >90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining
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