R&D Systems™ Recombinant Human B7-H7/HHLA2 Fc Chimera Protein

Product Code.
18379287	50ug; Carrier Free

Product Code. 18379287 Supplier R&D Systems™ Supplier No. 8084B7050

Description

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility.

Measured by its ability to inhibit anti-CD3 antibody induced IL-2 secretion in human T lymphocytes. The ED50 for this effect is 0.075-0.75 μg/mL.

Specifications

• Accession Number: Q9UM44
• For Use With (Application): Bioactivity
• Formulation: Lyophilized from a 0.2 μm filtered solution in PBS.
• Gene ID (Entrez): 11148
• Molecular Weight (g/mol): M.W. (Observed): 90-100 kDa, reducing conditions; M.W. (theoretical): 64 kDa (monomer)
• Name: B7-H7 Fc Chimera
• Quantity: 50 μg
• Source: Human embryonic kidney cell, HEK293-derived human B7-H7/HHLA2 protein Human B7-H7/HHLA2 (Ile23-Asn344) (N-terminus) Accession # Q9UM44 IEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
• Structural Form: Disulfide-linked homodimer
• Endotoxin Concentration: <0.10 EU / 1 μg of the protein by the LAL method.
• Gene Symbol: HHLA2
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Reconstitution: Reconstitute at 100 μg/mL in PBS.
• Purity or Quality Grade: >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Protein: B7-H7/HHLA2