R&D Systems™ Recombinant Human B7-H4 Protein Fc Chimera

Product Code.	Quantity	unitSize
18397437	50 μg	50µg

Product Code. 18397437 Supplier R&D Systems™ Supplier No. 8870B7050

Description

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility.

Measured by its ability to inhibit anti-CD3 antibody induced IL-2 secretion in human T lymphocytes. The ED50 for this effect is 0.1-0.5 μg/mL.

Specifications

• Accession Number: Q7Z7D3
• For Use With (Application): Bioactivity
• Formulation: Lyophilized from a 0.2 μm filtered solution in PBS.
• Gene ID (Entrez): 79679
• Molecular Weight (g/mol): M.W. (theoretical): 52 kDa
• Quantity: 50 μg
• Source: Human embryonic kidney cell, HEK293-derived human B7-H4 protein Human B7-H4 (Phe29-Ala258) (N-terminus) Accession # Q7Z7D3 IEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
• Endotoxin Concentration: <0.10 EU / 1 μg of the protein by the LAL method.
• Gene Alias: B7h.5, B7H4, B7-H4, B7H4T-cell costimulatory molecule B7x, B7S1, B7S1VCTN1, B7x, B7XPRO1291, FLJ22418, Immune costimulatory protein B7-H4, Protein B7S1, T cell costimulatory molecule B7x, V-set domain containing T cell activation inhibitor 1, V-set domain-containing T-cell activation inhibitor 1, Vtcn1
• Common Name: B7-H4
• Gene Symbol: VTCN1
• Biological Activity: Measured by its ability to inhibit anti-CD3 antibody induced IL-2 secretion in human T lymphocytes. The ED50 for this effect is typically 0.1-0.5μg/mL.
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Reconstitution: Reconstitute at 100 μg/mL in PBS.
• Expression System: Human embryonic kidney cell, HEK293-derived Human B7-H4 (Phe29-Ala258) Accession # Q7Z7D3, N-terminus; IEGRMD; Human IgG1 (Pro100-Lys330), C-terminus
• Purity or Quality Grade: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
• Protein: B7-H4