R&D Systems™ Recombinant Human alpha-L-Iduronidase/IDUA Avi Protein, CF

Product Code. 30279913

Brand: R&D Systems™ AVI11613010

Description

Recombinant Protein

Measured by its binding ability in a functional ELISA. Recombinant Human alpha-L-Iduronidase/IDUA Fc Chimera Avi-tag binds to Human alpha -L-Iduronidase/IDUA Antibody (Catalog # AF4119 ) with an ED50 of 2.00-20.0 ng/mL. Measured by its ability to cleave a fluorogenic substrate, 4-Methylumbelliferyl alpha -L-iduronide. The specific activity is >4500 pmol/min/μg, as measured under the described conditions.

Specifications

• For Use With (Application): Bioactivity, Enzyme Activity
• Formulation: Supplied as a 0.2 μm filtered solution in Sodium Acetate, NaCl and Glycerol.
• Gene ID (Entrez): 3425
• Molecular Weight (g/mol): M.W.-theoretical: 98 kDa, under reducing conditions, M.W.-observed: 104-115 kDa, under reducing conditions
• Quantity: 10 μg
• Source: Chinese Hamster Ovary cell line, CHO-derived human alpha-L-Iduronidase/IDUA protein Human IDUA (Ala26-Pro653) (N-terminus) Accession # P35475.2 Human IgG1 (Pro100-Lys330) Avi-tag (C-terminus)
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after opening.
• Endotoxin Concentration: <0.10 EU per 1 μg of the protein by the LAL method.
• Gene Alias: alphaLIduronidase, IDA, IDUA, MPS1, MPSI
• Conjugate: Biotin
• Protein: alpha-L-Iduronidase/IDUA