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DiscoverX Ready-to-Assay™ Y4 Neuropeptide Y Receptor Frozen Cells

Product Code. 17305369
Encompass
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Quantity:
2 Vials of Cells
Unit Size:
2 ampoules
This item is not returnable. View return policy

Product Code. 17305369

Brand: DiscoverX HTS204RTA

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This item is not returnable. View return policy

Description

The Ready-to-Assay™ Y4 Neuropeptide Y Receptor Frozen Cells measure NPY4R (GPCR) activation via an increase in intracellular calcium. Ready-to-Assay kits contain two vials of thaw-and-use cells.

The Ready-to-Assay™ Y4 Neuropeptide Y Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. peptide YY) based activation of NPY4R GPCR activity via detection of increasing levels of intracellular calcium. The included cells overexpress NPY4R alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of NPY4R , the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the cells in a convenient thaw-and-use format.

Specifications

Assay Entry Y4
For Use With (Application) Frozen Cells
Primary Agonist peptide YY
Quantity 2 Vials of Cells
Target Entry NPY4R
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