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DiscoverX Ready-to-Assay™ FFA3/GPR41 Free Fatty Acid Receptor Frozen Cells

Product Code. 17335269
Encompass
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Quantity:
2 Vials of Cells
Unit Size:
2 ampoules
This item is not returnable. View return policy

Product Code. 17335269

Brand: DiscoverX HTS135RTA

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This item is not returnable. View return policy

Description

The Ready-to-Assay™ FFA3/GPR41 Free Fatty Acid Receptor Frozen Cells measure FFAR3 (GPCR) activation via an increase in intracellular calcium. Ready-to-Assay kits contain two vials of thaw-and-use cells.

The Ready-to-Assay™ FFA3/GPR41 Free Fatty Acid Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. free fatty acids) based activation of FFAR3 GPCR activity via detection of increasing levels of intracellular calcium. The included cells overexpress FFAR3 alongside exogenous levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of FFAR3 , the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the cells in a convenient thaw-and-use format.

Specifications

Assay Entry FFAR3/GPR41
For Use With (Application) Frozen Cells
Primary Agonist free fatty acids
Quantity 2 Vials of Cells
Target Entry FFAR3
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