Invitrogen™ RCC1 Monoclonal Antibody (6B11E7)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA549237

Product Code. 17920741

Description

Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL. Positive Control - WB: human 293T whole cell, human A431 whole cell, human HepG2 whole cell, human Raji whole cell. IHC: human thyroiditis tissue, human colorectal adenocarcinoma tissue, human breast cancer tissue, human spleen tissue, human squamous cell lung carcinoma tissue. ICC/IF: A431 cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly.

Specifications

• Antigen: RCC1
• Classification: Monoclonal
• Concentration: 500 μg/mL
• Formulation: PBS with 4mg trehalose and no preservative
• Gene Accession No.: P18754
• Gene Symbols: RCC1
• Immunogen: E.coli-derived human RCC1 recombinant protein (Position: A14-S421).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: 6B11E7
• Conjugate: Unconjugated
• Gene: RCC1
• Gene Alias: 4931417M11Rik; AI326872; Cell cycle regulatory protein; chc1; chc1-a; chromosome condensation 1; chromosome condensation protein 1; fj77f08; guanine nucleotide-releasing protein; RanGEF; RCC1; rcc1.L; rcc1-a; rcc1-b; RCC1-I; Regulator of chromosome condensation; regulator of chromosome condensation 1; regulator of chromosome condensation 1 L homeolog; SNHG3-RCC1; SNHG3-RCC1 readthrough; wu:fj77f08; XELAEV_18012073mg; xrcc1; zgc:65796; zgc:77114
• Host Species: Mouse
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1104
• Content And Storage: -20°C
• Form: Lyophilized