Invitrogen™ RCAN1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA523027

Product Code. 13288058

Description

In Western blot, a band is seen at ~38 kDa, representing isoform RCAN1-1L.

The RCAN1 protein interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses.

Specifications

• Antigen: RCAN1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Rcan1
• Gene Alias: Adapt78; calcineurin inhibitor; calcipressin-1; calcium and oxidant-inducible mRNA; CALP1L; CSP1; Down syndrome candidate region 1; Down syndrome critical region gene 1; Down syndrome critical region homolog 1; Down syndrome critical region protein 1; Down syndrome critical region protein 1 homolog; DSC1; Dscr1; MCIP1; modulatory calcineurin-interacting protein 1; myocyte-enriched calcineurin-interacting protein 1; near DSCR proline-rich protein; Rcan1; RCN1; Regulator of calcineurin 1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1827, 54720
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 30% glycerol and 0.1% sodium azide
• Gene Accession No.: P53805, Q9JHG6
• Gene Symbols: Rcan1
• Immunogen: Synthetic peptide made to an internal portion of human RCAN1 (within residues 40-90).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG