Invitrogen™ Rattin Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA14359

Product Code. 11578860

Description

PA1-4359 detects Rattin (Humanin-like) from rat samples. PA1-4359 has been successfully used in Western blot procedures. PA1-4359 immunizing peptide corresponds to amino acid residues 20-35 from rat Rattin protein.

A novel rat gene, Rattin, encodes a peptide homologous to Humanin, a secreted peptide that specifically protects against neuronal cell death induced by beta-amyloid peptide (Ab) or by mutations causing early-onset familial Alzheimer's disease. Rattin is the prototype of a novel class of peptides, phylogenetically related to Humanin, endowed with protective activity not only against Ab but also toward excitotoxic neuronal death. The rat gene, Rattin, encodes a peptide of 38 residues (15 residues longer than Humanin) showing 73% identity in the conserved region to Humanin.

Specifications

• Antigen: Rattin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene Alias: Humanin homolog
• Immunogen: Synthetic Peptide: V(20) K R L E S P N K T R R P Y G A(35).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Target Species: Rat
• Product Type: Antibody
• Isotype: IgG