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Gibco™ Rat TPO (Thrombopoietin) Recombinant Protein, PeproTech®

E. coli Recombinant Protein

Brand:  Gibco™ 400-34-500UG

Additional Details : Weight : 0.16500kg

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Product Code. 17834563

  • £2070.00 / 500µg
Estimated Shipment: 09-08-2024
to see stock.

Description

Description

Thrombopoietin (TPO, THPO, MPL ligand, megakaryocyte colony-stimulating factor) is responsible for the generation of platelets through its action on hematopoietic cells committed to the megakaryocyte lineage. Binding of thrombopoietin to its receptor, MPL (CD110), initiates a signaling cascade via JAK/STAT, MAPK, and PI3K/AKT signaling pathways that leads to the proliferation and differentiation of megakaryocytes and, ultimately, to the production of platelets (thrombopoiesis). Thrombopoietin is constitutively produced by the liver and has a predicted molecular weight of 38 kDa.
Specifications

Specifications

P49745
protein with no preservative
18.7
500 μg
-20°C
<1 EU/μg
THPO
Unconjugated
SPVPPACDPR LLNKLLRDSY LLHSRLSQCP DVNPLSIPVL LPAVDFSLGE WKTQTEQSKA QDILGAVSLL LEGVMAARGQ LEPSCLSSLL GQLSGQVRLL LGALQGLLGT QLPPQGRTTA HKDPSALFLS LQQLLRGKVR FLLLVEGPAL CVRRTLPTTA VPSRTSQLLT LNKF
≥ 98% by SDS-PAGE gel and HPLC analyses.
Functional Assay
108348162, 81811
Rat TPO (Thrombopoietin)
E. coli
RUO
C-mpl ligand; Megakaryocyte colony-stimulating factor; megakaryocyte growth and development factor; megakaryocyte stimulating factor; Mgdf; MKCSF; ML; MPL ligand; Mpllg; MSA; Myeloproliferative leukemia virus oncogene ligand; prepro-thrombopoietin; TDH2A; THCYT1; THPO; Thrombopoietin; thyroid microsomal antigen; thyroid peroxidase; thyroperoxidase; Tpo; TPX
Rat
Recombinant
Lyophilized
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