Invitrogen™ RASGRF1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA593320

Product Code. 16558471

Description

Immunogen sequence: MQKGIRLNDG HVASLGLLAR KDGTRKGYLS KRSSDNTKWQ TKWFALLQNL LFYFESDSSS RPSGLYLLEG CVCDRAPSPK PALSAKEPLE KQHYFTVNFS HENQKALELR TEDAKDCDEW VAAIAHASYR TLATEHEALM QKYLHLLQIV ETEKTVAKQL RQQIEDGEIE IERLKAEITS LLKDNERIQS; Positive Samples: Mouse brain.

RASGRF1 is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. Studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory.

Specifications

• Antigen: RASGRF1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RASGRF1
• Gene Alias: AI844718; ASPP1; Cdc25; CDC25L; CDC25Mm; Gnrp; GRF1; GRF55; Grfbeta; guanine nucleotide exchange factor; guanine nucleotide-releasing factor 1; guanine nucleotide-releasing factor, 55 kD; guanine nucleotide-releasing protein; H-GRF55; KIAA0771; P140 Ras-GRF; p190; P190-A; p190RhoGEF; PP13187; PPP1R13B; Ras guanine release factor beta; Ras protein specific guanine nucleotide releasing factor 1; RAS protein-specific guanine nucleotide-releasing factor 1; Rasgrf1; ras-GRF1; Ras-specific guanine nucleotide-releasing factor 1; Ras-specific guanine nucleotide-releasing factor, CDC25 homolog; ras-specific nucleotide exchange factor CDC25
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 19417
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 2.39 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P27671
• Gene Symbols: RASGRF1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human RASGRF1 (NP_0011391201).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG