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Invitrogen™ RARB Recombinant Rabbit Monoclonal Antibody (K01_1X75)
Description
RARB Recombinant Monoclonal Antibody for Western Blot
Retinoic Acid (RA; active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells. The Retinoid X Receptors (RXRs) family (RXR alpha, beta, and gamma), preferentially bind 9-cis -RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer. RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors.
Specifications
Specifications
| Antigen | RARB |
| Applications | Western Blot |
| Classification | Recombinant Monoclonal |
| Clone | K01_1X75 |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | 50mM tris glycine with 150mM NaCl, 40% glycerol, 0.05% BSA and 0.01% sodium azide; pH 7.4 |
| Gene | RARB |
| Gene Accession No. | P10826 |
| Gene Alias | A830025K23; HAP; HBV-activated protein; hepatitis B virus activated protein; MCOPS12; NR1B2; nuclear receptor subfamily 1 group B member 2; RAR beta; Rarb; RAR-b; RAR-beta; RARbeta1; RAR-Beta2; RAR-Beta4; RAR-epsilon; retinoic acid; retinoic acid receptor; retinoic acid receptor beta; retinoic acid receptor, beta; retinoic acid receptor, beta polypeptide; RRB2 |
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