Invitrogen™ RAR gamma-1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5113593

Product Code. 17131454

Description

Immunogen sequence: YPGAGFPFAF PGALRGSPPF EMLSPSFRGL GQPDLPKEMA SLSVETQSTS For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. Predicted homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Sheep: 100%.

Retinoic acid, a metabolite of vitamin A, is necessary for normal organogenesis but acts as a teratogen at high levels during embryonic and fetal development. Retinoic acid functions through its interaction with the nuclear protein, retinoic acid receptor (RAR). RAR belongs to the steroid and thyroid hormone superfamily of nuclear receptor proteins which exert their effects by binding to specific DNA response elements, thus regulating gene expression in target cells. RAR exists as three major subtypes: alpha, beta and gamma. Two main isoforms of RAR gamma exist: RAR gamma-1 has been found to be predominantly expressed in skin, while RAR gamma-2 has been found early in embryogenesis and in embryonal carcinoma cells. RAR gamma is also known as RARD. The corresponding gene for the retinoic acid receptor gamma 1 is NR1B3.

Specifications

• Antigen: RAR gamma-1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Rarg
• Gene Alias: Nr1b3; Nuclear receptor subfamily 1 group B member 3; RAR gamma 2; RAR Gamma-1; RARC; RARD; Rarg; RAR-gamma; RARgamma2; retinoic acid; retinoic acid nuclear receptor gamma variant 1; retinoic acid nuclear receptor gamma variant 2; retinoic acid receptor; retinoic acid receptor gamma; retinoic acid receptor gamma 4; retinoic acid receptor, gamma
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 19411, 5916
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: P13631, P18911
• Gene Symbols: Rarg
• Immunogen: Synthetic peptide directed towards the N terminal region of human RARG (aa 20-69).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG