Invitrogen™ RAPSN Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5115824

Product Code. 17268603

Description

Antibody detects endogenous levels of total Rapsyn.

This gene encodes a member of a family of proteins that are receptor associated proteins of the synapse. The encoded protein contains a conserved cAMP-dependent protein kinase phosphorylation site, and plays a critical role in clustering and anchoring nicotinic acetylcholine receptors at synaptic sites by linking the receptors to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin. Mutations in this gene may play a role in postsynaptic congenital myasthenic syndromes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Specifications

• Antigen: RAPSN
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RAPSN
• Gene Alias: 43 kD receptor-associated protein of the synapse; 43 kda postsynaptic protein; 43 kDa receptor-associated protein of the synapse; 43kDa; 43kDa acetylcholine receptor-associated protein; acetylcholine receptor-associated 43 kda protein; AChR associated protein at synapses; acetylcholine receptor associated protein at synapses; 43kDa protein; likely to cluster nicotinic AChRs; CMS11; CMS1D; CMS1E; CMS4C; FADS; MGC3597; Nraps; Raps; Rapsn; rapsyn; receptor associated protein of the synapse; receptor-associated protein of the synapse; receptor-associated protein of the synapse, 43 kDa; receptor-associated protein of the synapse, 43kD; RING finger protein 205; RNF205; twitch once; two
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 19400, 362161, 5913
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P12672, Q13702
• Gene Symbols: RAPSN
• Immunogen: A synthesized peptide derived from human RAPSN(Accession Q13702), corresponding to amino acid residues E372-V412.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG