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Rapamycin, MedChemExpress

Product Code. 16451546
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Product Code. 16451546

Brand: Medchem Express HY10219

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Description

MedChemExpress Rapamycin (Sirolimus; AY 22989) is a potent and specific mTOR inhibitor with an IC50 of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator, an immunosuppressant.

Rapamycin (Sirolimus

Specifications

Chemical Name or Material Rapamycin
CAS 53123-88-9
Color White
Purity Grade Notes Research
Molecular Formula C51H79NO13
Quantity 500 mg
Synonym Sirolimus AY-22989
Solubility Information DMSO : 125 mg/mL (136.74 mM; Need ultrasonic) ∣Ethanol : 50 mg/mL (54.69 mM; Need ultrasonic)
SMILES O=C([C@@]1(O)[C@@H](CC[C@@H](C[C@@H](/C(C)=C/C=C/C=C/[C@H](C[C@@H](C)C([C@@H]([C@@H](/C(C)=C/[C@H]2C)O)OC)=O)C)OC)O1)C)C(N3CCCC[C@H]3C(O[C@@H](CC2=O)[C@@H](C[C@H]4C[C@H]([C@H](O)CC4)OC)C)=O)=O
Molecular Weight (g/mol) 914.17
Formula Weight 914.17
Percent Purity 98.0%
Grade Research
Physical Form Powder
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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