Invitrogen™ RAP1A Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA129451

Product Code. 11562342

Description

It is expected to cross-react with zebrafish and C. elegans based on sequence homology of 100% and 94%, respectively. PA1-29451 has been successfully used in Western blot applications where a band of 25 kDa is detected. Positive control: rat brain tissue extract.

The product of this gene belongs to the family of RAS-related proteins. These proteins share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between RAP proteins and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. The product of this gene counteracts the mitogenic function of RAS because it can interact with RAS GAPs and RAF in a competitive manner. Two transcript variants encoding the same protein have been identified for this gene.

Specifications

• Antigen: RAP1A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RAP1A
• Gene Alias: AI848598; C21KG; G-22K; GTP-binding protein; GTP-binding protein smg p21A; GTP-binding protein SMG-P21A; KREV1; Krev-1; rap 1A; RAP1; RAP1A; RAP-1A; RAP1A, member of RAS oncogene family; RAS-related protein 1a; ras-related protein Krev-1; Ras-related protein Rap-1A; RAS-related protein-1a; SMGP21
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 100351588, 109905, 295347, 5906
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.95 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: P62834, P62835, P62836
• Gene Symbols: RAP1A
• Immunogen: Synthetic peptide corresponding to a portion of human Rap1a. Peptide differs from Rap1b by two residues.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Rabbit
• Product Type: Antibody
• Isotype: IgG