Invitrogen™ RAMP3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5117067

Product Code. 17279563

Description

Positive Samples: MCF7, SW620, Mouse brain, Mouse skin, Mouse kidney, Mouse heart, Mouse eye, Rat brain, Rat lung Immunogen sequence: METGALRRPQ LLPLLLLLCG GCPRAGGCNE TGMLERLPLC GKAFADMMGK VDVWKWCNLS EFIVYYESFT NCTEMEANVV GCYWPNPLAQ GFITGIHRQF FSNCTVDRVH LEDPPDEV.

The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP3) protein, CRLR functions as an adrenomedullin receptor.

Specifications

• Antigen: RAMP3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Ramp3
• Gene Alias: AI850306; calcitonin receptor-like receptor activity modifying protein 3; calcitonin-receptor-like receptor activity-modifying protein 3; CRLR activity-modifying protein 3; Ramp3; receptor (calcitonin) activity modifying protein 3; receptor (G protein-coupled) activity modifying protein 3; receptor activity modifying protein 3; receptor activity-modifying protein 3; receptor-activity-modifying protein 3
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10268, 56089, 56820
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O60896, Q9JJ73, Q9WUP1
• Gene Symbols: Ramp3
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-118 of human RAMP3 (NP_0058471).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG