Invitrogen™ RALA Monoclonal Antibody (399527)

Rat Monoclonal Antibody

Brand:  Invitrogen™ MA561286

Product Code. 30534016

Description

Reconstitute at 0.5 mg/mL in sterile PBS.

Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. Plays a role in the early stages of cytokinesis and is required to tether the exocyst to the cytokinetic furrow. The RALA-exocyst complex regulates integrin-dependent membrane raft exocytosis and growth signaling. Key regulator of LPAR1 signaling and competes with GRK2 for binding to LPAR1 thus affecting the signaling properties of the receptor. Required for anchorage-independent proliferation of transformed cells.

Specifications

• Antigen: RALA
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with trehalose and no preservative
• Gene Accession No.: P11233, P63321, P63322
• Gene Symbols: Rala
• Immunogen: E. coli-derived recombinant human RalA, Met1-Leu206.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Western Blot
• Clone: 399527
• Conjugate: Unconjugated
• Gene: Rala
• Gene Alias: 3010001O15Rik; AW322615; MGC48949; Ral; -ral simian leukemia viral oncogene homolog A (ras related); RALA; Ral-a; ral-A protein; RALA Ras like proto-oncogene A; Ras family small GTP binding protein RALA; ras related GTP binding protein A; Rasl1; RAS-like protein A; RAS-like, family 1; ras-related protein Ral-A; v-ral simian leukemia viral oncogene homolog A (ras related)
• Host Species: Rat
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 56044, 5898, 81757
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Lyophilized