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RAE1 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA521739
Code : LD
Additional Details : Weight : 0.01000kg
Description
Recommended positive controls: HeLaS3, Molt-4, Raji. Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (100%), Xenopus laevis (100%), Pig (100%), Chicken (100%), Chimpanzee (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene.Specifications
RAE1 | |
Polyclonal | |
Unconjugated | |
RAE1 | |
3230401I12Rik; 41; D2Ertd342e; dJ481F12.3; dJ800J21.1; FLJ30608; HGNC:9828; homolog of yeast Rae1 (Bharathi) mRNA-associated protein of 41 kDa (Kraemer); MGC117333; MGC126076; MGC126077; MIG14; migration-inducing gene 14; MNRP; Mnrp41; mRNA export factor; mRNA export factor-like protein; mRNA export protein; mRNA-associated protein MRNP 41; mRNA-binding protein, 41-kD; MRNP41; OTTHUMP00000166110; rae1; RAE1 (RNA export 1, S.pombe) homolog; rae1 protein; rae1 protein homolog; RAE1 RNA export 1 homolog; RAE1 RNA export 1 homolog (S. pombe); ribonucleic acid export 1; RP4-800J21.2; zgc:56449; zgc:77723 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
8480 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunocytochemistry, Western Blot | |
1 mg/mL | |
PBS with 10% glycerol and 0.01% thimerosal; pH 7 | |
P78406 | |
RAE1 | |
Synthetic peptide corresponding to a region within amino acids 307 and 368 of RAE1 (Uniprot ID#P78406) | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |